Xiaochu Ding

Contact

xding@mtu.edu
906-487-2865
Chem Sci 701C

Research Assistant Professor

PhD, Chemistry, Michigan Technological University
M.S., Chemistry, Zhejiang University
B.E., Chemical Engineering, Southwest University for Nationalities

Research Interests

Design, synthesis and characterization of polymeric biomaterials to engineer elastomers, hydrogels, and nanomaterials
Biomaterials/cell interactions and biological properties in vitro and in vivo
Synthetic vascular grafts and drug delivery systems for arterial regeneration and ischemia

Recent Publications

Risley, Brandon B.§; Ding, Xiaochu§; Chen, Ying; Miller, Paula; Wang, Yadong*. “Citrate crosslinked poly(glycerol sebacate) with tunable elastomeric properties”. Macromolecular Bioscience, 2020, accepted.
Chen, Ying; Miller, Paula G.; Ding, Xiaochu; Stowell, Chelsea E.T.; Kelly, Katie M.; Wang, Yadong*. “Chelation crosslinking of elastomers”. Advanced Materials, 2020, 32: 2003761.
Li, Hui; Herck, Simon Van; Liu, Yongjun; Hao, Yanyun; Ding, Xiaochu; Nuhn, Lutz; Zhong, Zifu; Combes, Francis; Sanders, Niek N.; Lienenklaus, Stefan; Koker, Stefaan D.; David, Sunil A.; Wang, Yadong; De Geest, Bruno G.; Zhang, Zhiyue. “Imidazoquinoline-conjugated degradable coacervate conjugate for local cancer immunotherapy.” ACS Biomaterials Science and Engineering, 2020, 6(9): 4993.
Ding, Xiaochu; Chen, Ying; Chao, Corson; Wu, Yen-Lin; Wang, Yadong*. “Control the mechanical properties and degradation of poly(glycerol sebacate) by substitution of the hydroxyl groups with palmitates”. Macromolecular Bioscience, 2020, 20(9): 2000101.
Fu, Jiayin; Ding, Xiaochu; Stowell, Chelsea E.T.; Wu, Yen-Lin; Wang, Yadong*. “Slow degrading poly(glycerol sebacate) derivatives improve vascular graft remodeling in a rat carotid artery interposition model”. Biomaterials, 2020, 257: 120251.
Ding, Xiaochu; Gao, Jin; Acharya, Abhinav P; Little, Steven R.; Wang, Yadong*. “Azido-functionalized polyurethane designed for making tunable elastomers by click chemistry.” ACS Biomaterials Science & Engineering, 2020, 6 (2): 852.
Ding, Xiaochu; Miller, Paula G.; Hwang, Mintai Peter; Fu, Jiayin; Wang, Yadong*. “Scale-up synthesis of a polymer designed for protein therapy.” European Polymer Journal, 2019, 117: 353.
Lee, Kee-Won; Gade, Piyusha S; Dong, Liwei; Zhang, Zhaoxiang; Aral, Ali Mobin; Gao, Jin; Ding, Xiaochu et. al. “A biodegradable synthetic graft for small arteries matches the performance of autologous vein in rat carotid arteries.” Biomaterials, 2018, 181: 67.
Hwang, Mintai Peter; Ding, Xiaochu; Gao, Jin; Acharya, Abhinav P.; Little, Steven R; Wang, Yadong*. “A biocompatible betaine-functionalized polycation for coacervation.” Soft Mater, 2018, 14 (3): 387.
Ding, Xiaochu; Wu, Yen-Lin, Gao, Jin; Wells, Albin; Lee, Keewon; Wang, Yadong*. “Tyramine functionalization of poly(glycerol sebacate) increases the elasticity of the polymer.” Journal of Materials Chemistry B, 2017, 5: 6097.
Ding, Xiaochu; Wang, Yadong*. “Weak bond-based injectable and stimuli responsive hydrogels for biomedical applications.” Journal of Materials Chemistry B, 2017, 5 (5): 887 (Invited Review, selected as a hot article by this journal)
Acharya, Abhinav P; Sinha, Mantosh; Ratay, Michelle L; Ding, Xiaochu; Balmert, Stephen C; Workman, Creg J; Wang, Yadong; Vignali, Dario A A; Little, Steve R*. “Localized multi-component delivery platform generates local and systemic anti-tumor immunity.” Advanced Functional Materials, 2017, 27 (5): 1604366.
Ding, Xiaochu; Gao, Jin; Wang, Zhouguang; Awada, Hassan; Wang, Yadong*. “A shear-thinning hydrogel that extends in vivo bioactivity of FGF2.” Biomaterials, 2016, 111: 80.
Ding, Xiaochu; Gao, Jin; Awada, Hassan; Wang, Yadong*. “Dual physical dynamic bond-based injectable and biodegradable hydrogel for tissue regeneration.” Journal of Materials Chemistry B, 2016, 4 (6): 1175.
Wang, Yadong*; Friberg, Thomas R*; Sinha, Mantosh; Awada, Hassan; Ding, Xiaochu. “An injectable, biodegradable, and biocompatible reverse thermal gel designed for controlled intra-vitreal drug delivery.” Investigative Ophthalmology & Visual Science, 2016, 57 (12).
Ding, Xiaochu; Vegesna, Giri K.; Meng, Hao; Winter, Audra; Lee, Bruce P.*. “Nitro-group functionalization of dopamine and its contribution to the viscoelastic properties of catechol-containing nanocomposite Hydrogels.” Macromolecular Chemistry and Physics, 2015, 216: 1109.
Yang, Ying; Ding, Xiaochu; Urban, Marek W*. “Chemical and physical aspects of self-healing materials.” Progress in Polymer Science, 2015, 49: 34.
Xiang, Xu; Ding, Xiaochu*; Moser, Trevor; Gao, Qi; Shokuhfar, Tolou; Heiden, Patricia A*. “Peptidedirected self-assembly of polymeric nanoparticles part II: Effects of nanoparticle composition on assembly behavior and multiple drug loading ability.” Macromolecular Bioscience, 2015, 15 (4): 568.
Xiang, Xu; Ding, Xiaochu; Chen, Ning; Zhang, Beilu; Heiden, Patricia A*. “End group polarity and block symmetry effects on cloud point and hydrodynamic diameter of thermoresponsive block copolymers.” Journal of Polymer Science, Part A: Polymer Chemistry, 2015, 53 (24): 2838.
Ding, Xiaochu*; Janjanam, Jagadeesh; Thompson, Marty; Tiwari, Ashutosh; Heiden, Patricia A*. “Peptide-directed self-assembly of polymeric nanoparticles part I: Design and self-assembly of peptidecopolymer conjugates into nanoparticle fibers and 3D scaffolds.” Macromolecular Bioscience, 2014, 14 (6): 853.
Ding, Xiaochu*; Heiden, Patricia A*. “Recent developments in molecularly imprinted nanoparticles by surface imprinting techniques.” Macromolecular Materials and Engineering, 2014, 299 (3): 268.
Jin, Dalai; Liu, Ruirui; Ding, Xiaochu et al. “Fabrication and electrochemical performance of nanofibrous micro-frameworks of a-MnO2.” Particuology, 2014, 17: 54.
Ding, Xiaochu; Meneses, Martha Barajas; Richter, Dana L.; Heiden, Patricia A*. “Comparison of leaching of copper oxide nanoparticles and ammoniacal copper salt from wood.” Macromolecular Materials and Engineering, 2013, 289 (12): 1335.
Ding, Xiaochu*; Richter, Dana L.; Matuana, Laurent M.; Heiden, Patricia A*. “Efficient one-pot synthesis and loading of self-assembled amphiphilic chitosan nanoparticles for low-leaching wood preservation.” Carbohydrate Polymers, 2011, 86 (1): 58.