Yan Zhang

Contact

Ph.D. Research Assistantship
- Previous experiences in molecular biology, cell biology, and animal studies are preferred
- Send CV to yzhang49@mtu.edu

The role of innate immunity in the pathological microenvironment of autosomal dominant polycystic kidney disease (ADPDK)
The potential therapeutic effects of manipulating innate immunity
Determining the function of polycystin-1 encoded by the PKD1 gene

Recent Publications

Parnell, S.C., Raman, A., Zhang Y., Daniel, E.A., Dai, Y., Khanna, A., and others (2022) Expression of active B-Raf proto-oncogene in kidney collecting ducts induces cyst formation in normal mice and accelerates cyst growth in mice with polycystic kidney disease. Kidney International, 102 (5) 1103-1114 Read more
Zhang, Y., Daniel, E. A., Metcalf, J., Dai, Y., Reif, G. A., & Wallace, D. P. (2022). CaMK4 overexpression in polycystic kidney disease promotes mTOR-mediated cell proliferation. Journal of Molecular Cell Biology, 14(7), mjac050. Read more
Zhang, Y., Dai, Y., Raman, A., Daniel, E., Metcalf, J., Reif, G., ... & Wallace, D. P. (2020). Overexpression of TGF-β1 induces renal fibrosis and accelerates the decline in kidney function in polycystic kidney disease. American Journal of Physiology-Renal Physiology, 319(6), F1135-F1148. Read more
Zhang, Y., Reif, G., & Wallace, D. P. (2020). Extracellular matrix, integrins, and focal adhesion signaling in polycystic kidney disease. Cellular signalling, 72, 109646. Read more
Omede, F., Zhang, S., Johnson, C., Daniel, E., Zhang, Y., Fields, T. A., ... & Stubbs, J. R. (2020). Dietary phosphate restriction attenuates polycystic kidney disease in mice. American Journal of Physiology-Renal Physiology, 318(1), F35-F42. Read more